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1.
Cross reactive T cells hold up against Omicron.
Flemming, Alexandra.
Nat Rev Immunol ; 22(3): 146, 2022 03.
Article in English | MEDLINE | ID: covidwho-2237772
2.
First glimpses into the mechanisms of Long COVID.
Flemming, Alexandra.
Nat Rev Immunol ; 22(3): 146, 2022 03.
Article in English | MEDLINE | ID: covidwho-2230032
3.
Rejuvenation through checkpoint inhibitors?
Flemming, Alexandra.
Nat Rev Immunol ; 22(12): 718, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2151047

Subject(s)
Immune Checkpoint Inhibitors , Rejuvenation , Humans
4.
Fungal lipase dampens DC response.
Flemming, Alexandra.
Nat Rev Immunol ; 22(12): 718, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2151046
5.
'Prime and spike' induces mucosal immunity and reduces SARS-CoV-2 transmission.
Flemming, Alexandra.
Nat Rev Immunol ; 22(12): 718, 2022 Dec.
Article in English | MEDLINE | ID: covidwho-2106417

Subject(s)
COVID-19 , SARS-CoV-2 , Humans , Immunity, Mucosal , Spike Glycoprotein, Coronavirus , Antibodies, Viral
6.
Diabetes enhances viral loads in COVID-19.
Flemming, Alexandra.
Nat Rev Immunol ; 22(7): 410, 2022 07.
Article in English | MEDLINE | ID: covidwho-1991618

Subject(s)
COVID-19 , Diabetes Mellitus , Humans , RNA, Viral , SARS-CoV-2 , Viral Load
7.
Epitope mapping of spike identifies variant-resistant antibodies
Flemming, Alexandra.
Nature reviews. Immunology ; : 1-1, 2021.
Article in English | EuropePMC | ID: covidwho-1451217

ABSTRACT

One of the biggest concerns in the ongoing COVID-19 pandemic is the potential emergence of SARS-CoV-2 variants that evade immunity. A report in Science now presents a comprehensive map of antibody binding sites of the SARS-CoV-2 spike protein, which was generated using several hundred monoclonal antibodies (mAbs).

8.
RNA exosome essential for early B cell development.
Flemming, Alexandra.
Nat Rev Immunol ; 22(8): 462-463, 2022 08.
Article in English | MEDLINE | ID: covidwho-1972620

Subject(s)
Exosome Multienzyme Ribonuclease Complex , Exosomes , Exosome Multienzyme Ribonuclease Complex/genetics , Exosome Multienzyme Ribonuclease Complex/metabolism , Exosomes/metabolism , Humans , RNA , RNA Stability , Transcription, Genetic
9.
Omicron alone provides limited cross-protection.
Flemming, Alexandra.
Nat Rev Immunol ; 22(7): 410, 2022 Jul.
Article in English | MEDLINE | ID: covidwho-1956408
10.
Vaccines only partially protect against Long COVID.
Flemming, Alexandra.
Nat Rev Immunol ; 22(7): 410, 2022 07.
Article in English | MEDLINE | ID: covidwho-1956407

Subject(s)
COVID-19 , Vaccines , COVID-19/complications , COVID-19/prevention & control , COVID-19 Vaccines , Humans , SARS-CoV-2 , Post-Acute COVID-19 Syndrome
11.
Gut commensals promote antiviral immunity via extracellular vesicles.
Flemming, Alexandra.
Nat Rev Immunol ; 22(7): 410, 2022 07.
Article in English | MEDLINE | ID: covidwho-1921624

Subject(s)
Antiviral Agents , Extracellular Vesicles , Humans , Symbiosis
12.
New tool to investigate spike-specific CD4+ T cells.
Flemming, Alexandra.
Nat Rev Immunol ; 22(5): 275, 2022 05.
Article in English | MEDLINE | ID: covidwho-1782381

Subject(s)
SARS-CoV-2 , Spike Glycoprotein, Coronavirus , CD4-Positive T-Lymphocytes , Humans
13.
Are variant-specific vaccines warranted?
Flemming, Alexandra.
Nat Rev Immunol ; 22(5): 275, 2022 05.
Article in English | MEDLINE | ID: covidwho-1782380

Subject(s)
Antibodies, Viral , Vaccines , Humans , Vaccines, Inactivated
14.
Do individuals who have recovered from COVID-19 still benefit from being vaccinated?
Flemming, Alexandra.
Nat Rev Immunol ; 22(5): 275, 2022 05.
Article in English | MEDLINE | ID: covidwho-1783996

Subject(s)
COVID-19 , COVID-19/prevention & control , Humans , SARS-CoV-2 , Vaccination
15.
Bispecific agonist boosts anti-tumour T cells via GITR.
Flemming, Alexandra.
Nat Rev Immunol ; 22(4): 208, 2022 04.
Article in English | MEDLINE | ID: covidwho-1783995

Subject(s)
Immunotherapy , T-Lymphocytes, Regulatory , Humans
16.
Omicron, the great escape artist.
Flemming, Alexandra.
Nat Rev Immunol ; 22(2): 75, 2022 02.
Article in English | MEDLINE | ID: covidwho-1619783

Subject(s)
COVID-19 , Humans , SARS-CoV-2
17.
Cross-reactive memory T cells abort SARS-CoV-2 infection.
Flemming, Alexandra.
Nat Rev Immunol ; 22(1): 5, 2022 01.
Article in English | MEDLINE | ID: covidwho-1555398
18.
MAIT cells boost adenovirus-induced CD8+ T cells.
Flemming, Alexandra.
Nat Rev Immunol ; 21(3): 134-135, 2021 03.
Article in English | MEDLINE | ID: covidwho-1550309

Subject(s)
Mucosal-Associated Invariant T Cells , Adenoviridae , CD8-Positive T-Lymphocytes , Genetic Vectors , Immunogenicity, Vaccine
19.
Does IgE sialylation hold the key to allergy?
Flemming, Alexandra.
Nat Rev Immunol ; 20(7): 408-409, 2020 07.
Article in English | MEDLINE | ID: covidwho-1550298

Subject(s)
Hypersensitivity , Immunoglobulin E , Humans , Virulence
20.
Tumours use NETs as physical shields.
Flemming, Alexandra.
Nat Rev Immunol ; 20(6): 352-353, 2020 06.
Article in English | MEDLINE | ID: covidwho-1550294

Subject(s)
Extracellular Traps , Neoplasms , Chemokines , Humans , Receptors, Chemokine
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